Publications | Welcome to Dr. Barla's Research Group

39. Highly Diastereoselective Synthesis of Trifluoromethylated Spirocyclopropanes from 2-(2′-Ketoalkyl)-1,3-Indandiones and CF3-Imidoyl Sulfoxonium Ylides

Pal, B. K.; Sahoo, S.; Thirupathi, B

Journal of Organic Chemistry, 2026,

https://doi.org/10.1021/acs.joc.6c01506

38. Ynones-Triggered Ring Expansion of Indandiones: Transition-Metal-Free Access to Benzoannulated Seven-Membered Rings

Sahil Mondal, Sayanta Roy, Priyanka Priyadarshini, Tarun Kumar Roy and Barla Thirupathi

Chem. Commun. 2026; https://doi.org/10.1039/D6CC05068A

37. Total Synthesis as a Critical Tool for Structural Revision of Natural Products

Patra, N.; Panigrahi, A.; Mandal, S.; Thirupathi B

Chem. Commun. 2026; https://doi.org/10.1039/D6CC05068A

36. A Formal (4+ 3) Strain-Release Annulation of Bicyclo [1.1. 0] butanes Enables Access to Azabicyclo [4.1. 1] octanes

Kundu, S.; Kisan, P.; Malya, N.; Mudedla, S. K.; Thirupathi B

ChemRxiv, 2026,

(doi: 10.26434/chemrxiv.15001032/v2) (Preprint)

35. Ynones as Versatile Electrophiles for the Divergent Synthesis of 4H-Chromenes and 1,4-Dihydroquinolines

Mishra, G.; Potnuru, I.; Muduli, G.; Thirupathi B.

Organic & Biomolecular Chemistry, 2026

(doi: 10.1039/D6OB00097E).

34. Synthesis of Spiro[indane-1,3-dione-2-pyrrolidines] by the Reaction of 2-(2′-Ketoalkyl)-1,3-Indandiones with Triazinanes

Pal, B. K.; Sahoo, S.; Mondal S., Thirupathi, B

Journal of Organic Chemistry, 2026, 91, 3239–3245.

https://doi.org/10.1021/acs.joc.5c02934

33. Collective Total Synthesis of (+)- and (−)-Baoslingzhines F–H, (+)- and (−)-Chizhiene C, and (+)- and (−)-Lingzhines E and F,

Patra, N.; Akshaya, S.; Goshwami, S.; Sanker, H.; D., Ruthrotha S. B., Thirupathi, B.

Organic Letters, 2026, 28, 1090–1094.

https://doi.org/10.1021/acs.orglett.5c05297

32. DABCO-catalysed highly diastereoselective synthesis of 1,3-indandione containing fully saturated spirocyclopentanes involving 2-(2′-ketoalkyl)-1,3-indandiones and nitrostyrenes,

Mishra, G.; Bobonga, M. S.; Islam, K.; Thirupathi, B.

RSC Advances, 2025, 15, 30768-30780

https://doi.org/10.1039/d5ra04224k

31. Total Synthesis, Determination of Absolute Configuration, Antibacterial Efficacy of Colletotrichumolide, and Its 3R-Diastereomer

Mandal, S.; Kundu, S.; Ginopragathish, B.; Neelam, Chakrabarty, A.; Moitra, P.; Thirupathi, B.

Journal of Organic Chemistry, 2025, 90, 7902–7909

https://doi.org/10.1021/acs.joc.5c00832

30.Kobayashi’s Aryne Precursor for the One-Step Synthesis of Anthraquinones and Its Application to the Total Synthesis of Chrysophanol, Danthron, and Physcion

Kundu, S.; Mandal, S.; Thirupathi, B.

Journal of Organic Chemistry, 2025, 90, 2472–2478.
https://doi.org/10.1021/acs.joc.4c03041

29. Synthesis of Sulfone Containing-Spirocycles, -Pentafulvene Dyes and Their Photophysical Properties (Invited Article),

Mishra, G.; Indu, P.; Sasmal, M.; Thirupathi, B.

European Journal of Organic Chemistry, 2025, e202401311
https://doi.org/10.1002/ejoc.202401311

28. Rapid Assembly of 1,3-Dicarbonyl Fused 5-phenyl-1-Azabicyclo[3.1.0]hexanes and Their Cytotoxic Activities

Pal, B. K.; Sahoo, K.; Sourav D., Ruthrotha S. B., Thirupathi, B.

Organic Letters, 2025, 27, 761–766.
https://doi.org/10.1021/acs.orglett.4c04394

27. Synthesis and Functionalization of Natural Products with Light-Driven Reactions

Sahoo, K.; Mishra, G.; Thirupathi, B

Sustainable Green Catalytic Processes, 2024, 183
DOI: 10.1002/9781394212767.ch9 Book chapter, ISBN: 9781394212552, Publisher John Wiley.

26. Synthesis of Spirocyclic-1,3-indandione Containing-Cyclopentenones and -Benzotropones

Mishra, G.; C. M, Y., Thirupathi, B.

Chemistry An Asian Journal, 2024, e202400667,
Doi: 10.1002/asia.202400667

25. A Three-Component Synthesis of Spiropyrrolines

Sahoo, K.; Patra, N.; Dandela, R. Thirupathi, B.

The Journal of Organic Chemistry. 2024, 89, 5337–5352.
https://doi.org/10.1021/acs.joc.3c02713

24. Total Synthesis and Determination of the Absolute Configuration of Berkeleylactone I:

(Highlighted in the Organic Chemistry Portal)

Sudip, M.; Dora, M.; Dileep, P.; Thirupathi, B.

The Journal of Organic Chemistry. 2024, 89, 4165–4175.
https://doi.org/10.1021/acs.joc.4c00178

23. Synform Interview of Barla Thirupathi as a Young Career Focus Presentation:

Thirupathi, B.

Synform 2024/03, A41–A43
DOI: 10.1055/s-0040-1720624

22. Total Synthesis, Revised Structure, and Biological Evaluation of Elgonene B and Analogues.

Sudip M., Dora M., Sourav D., Ruthrotha S. B., Thirupathi, B.

Journal of Natural Products, 2024, 87, 152–159
https://doi.org/10.1021/acs.jnatprod.3c00988

21. Synthesis of Highly Functionalized Spirocycles and Pentafulvene Containing Dyes Involving 2-(2'-ketoalkyl)-1,3-indandiones.

(Featured on the journal cover page)

Mishra, G.; Sasmal, M.; Chakraborty, A.; Thirupathi, B.

Chemistry—A European Journal, 2023, e202301976
https://doi.org/10.1002/chem.202301976Digital Object Identifier (DOI)

20. Cascade Nucleophilic Addition-Cyclic Michael Addition of Arynes, Indoles Bearing Michael Acceptor: A Strategy To Construct Pyrroloacridines, and Study of Their Physicochemical Properties.

Hazra, G.; Kundu, S.; Dandela, R.; Thirupathi, B.

Journal of Organic Chemistry 2023, 88, 8493–8504.
https://doi.org/10.1021/acs.joc.3c00462

19. Recent advances with cobalt-mediated asymmetric hydrogenations

Gurupada, H.; Dinesh, S.; Sahoo, K.; Thirupathi, B.

(Invited Review)

Results in Chemistry 2023, 5, 10084
10.1016/j.rechem.2023.100843

18. Synthesis of Fluorinated 1-(2-Benzyl)-phthalazinone, 1-Phthalazinamine, and 1-Alkoxy/Benzyloxy-Phthalazine Derivatives by Ultrasonication Method

(Invited article for the Special Issue on Chemical Synthesis and Catalysis in India)

Pothireddy, M.; Gurupada, H.; Vijaya Babu, P.; Thirupathi, B.*; Rambabu. D

Synlett 2022; 33(17): 1716-1722
10.1055/a-1846-5200

17. A Method to Access Highly Functionalized Dibenzobicyclo[3.2.1]octadienones: Application to the Construction of the 6/6/5/6/6 Carbon Skeleton of Rubialatin A

Hazra, G.; Mishra, G.; Dandela, R.; Thirupathi, B.

The Journal of Organic Chemistry 2022, 87, 18, 11925-11938
https://doi.org/10.1021/acs.joc.2c00340

16. Total Synthesis of Proposed Elgonene C and its (4R,5R)-Diastereomer

(Selected and featured on the journal front cover of the issue).

Sudip M., Thirupathi, B.

Org. Biomol. Chem., 2022, 20, 3922-3929.
https://doi.org/10.1039/d2ob00094f

15. Synthetic method to access fluorinated 2-benzylpyridines by using Negishi coupling reaction

Pothireddy, M.; Bhukta, S.; Vijaya Babu, P.; Thirupathi, B.; Rambabu. D

Synthetic Communications. 2022, 1-13
https://doi.org/10.1080/00397911.2022.2037651

14. Strategies for the Construction of γ-Spirocyclic Butenolides in Natural Product Synthesis

Sudip M., Thirupathi, B.

Org. Biomol. Chem., 2020, 18, 5287-5314
https://doi.org/10.1039/d0ob00954g

13. Syntheses and Biological Importance of Herboxidiene/GEX1A

Thirupathi, B*.; Zilla, M. K.

ChemistrySelect. 2019, 4, 11944-11958
https://doi.org/10.1002/slct.201902742

12. Total Synthesis of (+)-Sacrolide-A

(Top downloaded article among work published between January 2018 and December 2019 in its journal)

Thirupathi, B*.; Jena, B, K.

ChemistrySelect. 2019, 4, 2908-2911
https://doi.org/10.1002/slct.201900192Digital Object Identifier (DOI)

Postdoctoral & PhD publications

11. Useful Applications of Enantioselective (4+ 2)-Cycloaddition Reactions to the Synthesis of Chiral 1, 2-Amino Alcohols, 1, 2-Diamines, and β-Amino Acids
(K. M.; Reddy#.; Thirupathi, B#.; Corey, E. J. Org. Lett. 2017, 19, 4956-4957 (#Equal Contribution).

10. Acceleration of enantioselective cycloadditions catalyzed by second-generation chiral oxazaborolidinium triflimidates by biscoordinating lewis acids

(Thirupathi, B.; Breitler, S.; Reddy, K. M.; Corey, E. J. J. Am. Chem. Soc. 2016, 138, 10842-10845)

9. Cationic chiral fluorinated oxazaborolidines. More potent, second-generation catalysts for highly enantioselective cycloaddition reactions

(Reddy, K. M.; Bhimireddy, E.; Thirupathi, B.; Breitler, S.; Yu, S.; Corey, E. J. J. Am. Chem. Soc. 2016, 138, 2443-2453)

7. Chemoenzymatic total synthesis of four stereoisomers of centrolobine

(B. Nagarjuna, Thirupathi, B.; Mohapatra D. K. Tetrahedron Lett. 2015, 56, 4916–4918)

8. Gold-Catalyzed Hosomi-Sakurai Type Reaction for the Total Synthesis of Herboxidiene
(Thirupathi. B.; Mohapatra. D. K. Org. Biomol. Chem., 2016, 14, 6112-6224)

4. A Carbohydrate-Based Total Syntheses of (+)-Pyrenolide D and (−)-4-epi-Pyrenolide D

(Thirupathi. B.; P. Purushotam Reddy, Mohapatra. D. K. J. Org. Chem. 2011, 76, 9835−9840)

6. First total synthesis of cryptosporiopsin A

(Thirupathi. B.; Mohapatra. D. K. RSC Adv., 2014, 4, 8027-8030)

5. An Efficient Synthesis of Dibenzo[b,f]oxepins by Ring‐Closing Metathesis

(Bharath. Y, Thirupathi. B.; Gurram Ranjit and Mohapatra. D. K. Asian J. Org. Chem. 2013, 2, 848-851)

3. First Total Syntheses of (3R,5R)-Sonnerlactone and (3R,5S)-Sonnerlactone

(Thirupathi. B, Gundapaneni. R. R, Mohapatra. D. K. Synlett. 2011, 18, 2667-2670)

2. Stereoselective synthesis of four possible isomers of streptopyrrolidine

(Mohapatra. D. K., Thirupathi. B.; Das. P. P. and. Yadav. J. S. Beilstein J. Org. Chem. 2011, 7, 34–39)

Pal, B. K.; Sahoo, S.; Thirupathi, B​​

​Sahil Mondal, Sayanta Roy, Priyanka Priyadarshini, Tarun Kumar Roy and Barla Thirupathi

Patra, N.; Panigrahi, A.; Mandal, S.; Thirupathi B

Kundu, S.; Kisan, P.; Malya, N.; Mudedla, S. K.; Thirupathi B

Mishra, G.; Potnuru, I.; Muduli, G.; Thirupathi B.

Pal, B. K.; Sahoo, S.; Mondal S., Thirupathi, B

Patra, N.; Akshaya, S.; Goshwami, S.; Sanker, H.; D., Ruthrotha S. B., Thirupathi, B.

Mishra, G.; Bobonga, M. S.; Islam, K.; Thirupathi, B.

Mandal, S.; Kundu, S.; Ginopragathish, B.; Neelam, Chakrabarty, A.; Moitra, P.; Thirupathi, B.

Kundu, S.; Mandal, S.; Thirupathi, B.

Mishra, G.; Indu, P.; Sasmal, M.; Thirupathi, B.

Pal, B. K.; Sahoo, K.; Sourav D., Ruthrotha S. B., Thirupathi, B.

Sahoo, K.; Mishra, G.; Thirupathi, B

Mishra, G.; C. M, Y., Thirupathi, B.

Sahoo, K.; Patra, N.; Dandela, R. Thirupathi, B.

(Highlighted in the Organic Chemistry Portal)

Sudip, M.; Dora, M.; Dileep, P.; Thirupathi, B.

Thirupathi, B.

Sudip M., Dora M., Sourav D., Ruthrotha S. B., Thirupathi, B.

(Featured on the journal cover page)

Mishra, G.; Sasmal, M.; Chakraborty, A.; Thirupathi, B.

Hazra, G.; Kundu, S.; Dandela, R.; Thirupathi, B.

(Invited Review)

Hazra, G.; Mishra, G.; Dandela, R.; Thirupathi, B.

Sudip M., Thirupathi, B.

Pothireddy, M.; Bhukta, S.; Vijaya Babu, P.; Thirupathi, B.; Rambabu. D

Sudip M., Thirupathi, B.

Thirupathi, B*.; Zilla, M. K.

Thirupathi, B*.; Jena, B, K.

ChemistrySelect. 2019, 4, 2908-2911 https://doi.org/10.1002/slct.201900192Digital Object Identifier (DOI)

Postdoctoral & PhD publications

11. Useful Applications of Enantioselective (4+ 2)-Cycloaddition Reactions to the Synthesis of Chiral 1, 2-Amino Alcohols, 1, 2-Diamines, and β-Amino Acids (K. M.; Reddy#.; Thirupathi, B#.; Corey, E. J. Org. Lett. 2017, 19, 4956-4957 (#Equal Contribution).

(Thirupathi, B.; Breitler, S.; Reddy, K. M.; Corey, E. J. J. Am. Chem. Soc. 2016, 138, 10842-10845)

9. Cationic chiral fluorinated oxazaborolidines. More potent, second-generation catalysts for highly enantioselective cycloaddition reactions

(Reddy, K. M.; Bhimireddy, E.; Thirupathi, B.; Breitler, S.; Yu, S.; Corey, E. J. J. Am. Chem. Soc. 2016, 138, 2443-2453)

(B. Nagarjuna, Thirupathi, B.; Mohapatra D. K. Tetrahedron Lett. 2015, 56, 4916–4918)

8. Gold-Catalyzed Hosomi-Sakurai Type Reaction for the Total Synthesis of Herboxidiene (Thirupathi. B.; Mohapatra. D. K. Org. Biomol. Chem., 2016, 14, 6112-6224)

(Thirupathi. B.; P. Purushotam Reddy, Mohapatra. D. K. J. Org. Chem. 2011, 76, 9835−9840)

6. First total synthesis of cryptosporiopsin A

(Thirupathi. B.; Mohapatra. D. K. RSC Adv., 2014, 4, 8027-8030)

(Bharath. Y, Thirupathi. B.; Gurram Ranjit and Mohapatra. D. K. Asian J. Org. Chem. 2013, 2, 848-851)

(Thirupathi. B, Gundapaneni. R. R, Mohapatra. D. K. Synlett. 2011, 18, 2667-2670)

(Mohapatra. D. K., Thirupathi. B.; Das. P. P. and. Yadav. J. S. Beilstein J. Org. Chem. 2011, 7, 34–39)

(Thirupathi. B, Bharath, Y. Mohapatra. D. K. ARKIVOC 2016 (ii) 162-171)

Pal, B. K.; Sahoo, S.; Thirupathi, B

Sahil Mondal, Sayanta Roy, Priyanka Priyadarshini, Tarun Kumar Roy and Barla Thirupathi

ChemistrySelect. 2019, 4, 2908-2911
https://doi.org/10.1002/slct.201900192Digital Object Identifier (DOI)

11. Useful Applications of Enantioselective (4+ 2)-Cycloaddition Reactions to the Synthesis of Chiral 1, 2-Amino Alcohols, 1, 2-Diamines, and β-Amino Acids
(K. M.; Reddy#.; Thirupathi, B#.; Corey, E. J. Org. Lett. 2017, 19, 4956-4957 (#Equal Contribution).

8. Gold-Catalyzed Hosomi-Sakurai Type Reaction for the Total Synthesis of Herboxidiene
(Thirupathi. B.; Mohapatra. D. K. Org. Biomol. Chem., 2016, 14, 6112-6224)